Application

Nonfluorescent Ca²⁺ ionophore that can be used to calibrate the quantitation of cytoplasmic free Ca²⁺ with fluorescent probes.

Biochem/physiol Actions

Cell permeable: no

Reversible: no

Primary TargetCation ionophore

Product does not compete with ATP.

General description

Brominated analog of the widely used cation ionophore A23187 (Cat. No. 100105). Non-fluorescent and therefore suitable for use in the presence of fluorescent or metal-chelating probes.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Deber, C.M., and Hsu, L.C. 1986. Biochem. Biophys. Res. Commun. 134, 731.Deber, C.M., et al. 1985. Anal. Biochem.146, 349.

Packaging

1 mg in Plastic ampoule

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 months at -20°C.

Warning

Toxicity: Harmful (C)

assay	≥90% (HPLC)
color	yellow
form	solid
InChI key	LDXQFZZGVTWFCF-FHYGWRBKSA-N
InChI	1S/C29H36BrN3O6/c1-14-8-9-29(16(3)11-15(2)27(39-29)17(4)26(34)19-7-6-10-32-19)38-20(14)13-22-33-25-21(37-22)12-18(30)24(31-5)23(25)28(35)36/h6-7,10,12,14-17,20,27,31-32H,8-9,11,13H2,1-5H3,(H,35,36)/t14-,15-,16-,17-,20-,27+,29+/m1/s1
manufacturer/tradename	Calbiochem^®
Quality Level	100
shipped in	ambient
SMILES string	CNc1c(Br)cc2oc(C[C@H]3O[C@@]4(CC[C@H]3C)O[C@@H]([C@H](C)C[C@H]4C)[C@H](C)C(=O)c5ccc[nH]5)nc2c1C(O)=O
solubility	DMSO: 100 mg/mL
storage condition	desiccated (hygroscopic), protect from light, OK to freeze
storage temp.	2-8°C

Safety Data Sheet for 100107-1MG

Cas Number

76455-82-8

This product has met the following criteria to qualify for the following awards:

A23187; 4-Bromo-

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